Electrochemical Immunosensor for Analyte Detection

Contact: patents.ieo@ubd.edu.bn

Summary

The invention is related to a carbon nanofiber-based label free electrochemical immunosensor for sensitive detection of proteins in a fluid. The immunosensor is a modified carbon nano-fiber screen protected electrode (CNF-SPE) with a carboxyphenyl film activated by EDC/NHS. Monolayer of 4-aminophenylboronic acid coating was then fabricated onto the electrode to allow orientation of antibody via bonding of boronic acid-saccharide of oligosaccharide moiety located on the Fc region of antibody. The modified electrode is then used for the detection of a hormone such as a rbST in a fluid with a detection limit of 1pg/ml.

Status

UBD Ref: U35    Status: Granted

Filed: May-19, 2015    Granted: Mar-31, 2020

Inventors: Syazana Abdullah Lim; Minhaz Uddin Ahmed

U35-G-US; BN/N/2015/0094; US 15/131438; US 2016/0341,722 US 10,605,806