The invention is related to a carbon nanofiber-based label free electrochemical immunosensor for sensitive detection of proteins in a fluid. The immunosensor is a modified carbon nano-fiber screen protected electrode (CNF-SPE) with a carboxyphenyl film activated by EDC/NHS. Monolayer of 4-aminophenylboronic acid coating was then fabricated onto the electrode to allow orientation of antibody via bonding of boronic acid-saccharide of oligosaccharide moiety located on the Fc region of antibody. The modified electrode is then used for the detection of a hormone such as a rbST in a fluid with a detection limit of 1pg/ml.


UBD Ref No: U35    Status: Granted

Inventors: Syazana Abdullah Lim, Minhaz Uddin Ahmed

Documents: U35 G US, BN/N/2015/0094, US 15/131438, US 2016/0341,722, US 10,605,806

  • United States

    Filed: Apr 18, 2016

    Granted: Mar 31, 2020